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EhlersDanlos syndrome needs to be considered when, in the absence of another explanation, one or more of the following occur: late walking with joint hypermobility abnormal bruising and bleeding unexplained vessel rupture or dissection tissue fragility, atrophic scarring or skin hyperextensibility symptomatic joint hypermobility dislocations Hollow organ rupture Prognosis for Ehlers-Danlos Syndrome: Life span is usually normal with most types