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Recently, a similar phenotype produced by e-cigarettes in rats showed fibrosis, inflammation, and oxidative stress, but with cardiac hypertrophy ( Cardiovascular Studies of Smokers Using e-Cigarettes as a Tool for Smoking Cessation A meta-analysis of cardiovascular outcomes of smokers switching from traditional cigarettes to e-cigarettes did not show any improvement in stroke, myocardial infarction, or coronary heart disease outcomes (200)

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