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A climate of generalized chronic inflammation is then created, characterized by an increase in several inflammatory markers (IL-6, CRP, ICAM) and the recruitment of immune cells to the surface of blood vessels, two phenomena that contribute to the development of atherosclerosis

Djarum Black cigarettes produced for consumption in Indonesia contain a significantly higher quantity of tar and nicotine, 25 mg and 1 } : CS1 maint: DOI inactive as of November 2025 (link) "Kretek Cigarettes and Particulate Matter EmissionsAn Aerosol Spectrometric Study on Typical Indonesian Brands Flavored With Cloves"