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Figure 1 Mechanistically, N-3 PUFA prevented inflammatory and autoimmune responses mainly via anti-inflammatory and immune-modulating effects as it suppressed pro-inflammatory cytokine production, lymphocyte proliferation, cytotoxic T cell activity, natural killer cell activity, macrophage-mediated cytotoxicity, neutrophil/monocyte chemotaxis, MHC Class II expression, and antigen presentation (2138)