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( Fungi are also an important group in the microbial composition of tobacco leaves ( 3 CFU/g to 3 10 3 CFU/g and can reach up to 8 10 3 CFU/g in the leaves collected from a manufacturing plants ( Alternaria , Phoma , Cercospora , Aspergillus and Rhizopus on tobacco leaves during curing ( Cladosporium , Epicoccum , Trichoderma , Nigrospora , Penicillium , Chaetomium and Fusarium are most frequently isolated and cultured from flue-cured and non-flue-cured tobacco leaves (Yuan et al., 2018