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The combination can cause unpredictable physical and mental effects

Ligero Ligero (pronounced "lee-HAIR-oh") is a type of tobacco leaf found near the top of each tobacco plant

Today, we would not do that, admits Murch

Many of these harm reduction studies did not consider if cannabis could also be combined with alcohol and other drugs as complements [16], either to enhance overall effects [17] or more pragmatically, intoxication from the use of one drug leads to use of an additional drug, or greater availability or more permissive attitudes encourage wider poly drug use [17, 18], with important implications for overall drug harm [19,20,21,22,23,24,25]