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For external validation of the model in the Tehran Lipid and Glucose Study (TLGS), the area under the curve (AUC) and the HosmerLemeshow (HL) goodness-of-fit test was performed for discrimination and calibration, respectively 25

Manufacturers consider: Target market preferences Cost of production Competitor pack sizes Retail shelf compatibility Regulation compliance As a result, pack sizes continue to evolve with market demand and legal requirements