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Food and Drug Administration (FDA) classifies marijuana as a Schedule I substance

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Sample size An initial sample size calculation used the estimate of the within-arm SD of cigarettes per day from a pilot study (5.1 (95% CI [3.7, 8.2]: Additional File 1), which indicated that a sample size of 206 participants would give 80% power at the 5% significance level and a two-sided test to detect a difference of two cigarettes per day

The large volume of water and any chemicals present can harm the biological process of your ATU