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Marketers spend plenty of time defending their brands against copycats, but it is not often that a product copycats itself

American Spirit cigarettes may be more addictive than other cigarettes and many varieties of the brand have high levels of nicotine, according to one study on the issue

It has also been shown that cbNPs accumulate in antigen-presenting dendritic cells derived from emphysematous lung tissue of smokers [73] and that cigarette smoke triggers the NLRP3 inflammasome [63], which is again consistent with the observation that IL-1 levels are elevated in smokers lungs [19]