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The feelings of nicotine patches or gum may wear off Factors that may affect nicotine levels Other factors may impact the speed nicotine and cotinine leave your system, including: The amount you consume: The amount of cotinine you have in your urinemay relate Trusted Source PubMed Central Go to sourceto how much nicotine you consumed

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Others have delved into the longer-term effects of the chemicals in cigarette butts, finding that after 28 days of exposure freshwater rainbow trout ended up weighing less while Mediterranean mussels absorbed 22 compounds, including some classified as potentially toxic to humans or wildlife