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Our study was designed to test the hypothesis that tobacco smoke introduces exogenous stimulisuch as physicochemical agents or microbial productsthat activate innate and structural airway cells, resulting in the release of inflammatory cytokines and the creation of a pro-inflammatory microenvironment

For example, one needs to first measure the fresh air in an indoor space, a location where you know smoking has not taken place (i.e hallway or living area)

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Rummage your way through a few dozen things you find there