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The international trade in enslaved people from Africa operated from the 1500s to the 1800s, and the majority of the nine to 12 million enslaved people transported from Africa to the Americas were brought to Brazil and the Caribbean, where the climate was suitable for growing cash crops like chocolate, coffee, indigo, and, especially starting in the 1600s, sugarcane

But as the sex ratio became more balanced in the early eighteenth century and many enslaved men and women established families, an increasing number lived in separate dwellings

**Cambodia National Authority for Combating Drugs passed a circular banning the importation, trafficking, sale, and use of HTP on 18 March 2021

While the agency's action allows them to be legally marketed in the U.S