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Potential oral health risks associated with oral nicotine pouches Even without tobacco, oral nicotine pouches can still affect your mouth in the following ways: Gum irritation Placing oral nicotine pouches against your gums can cause localized irritation

Propylene glycol and glycerol can produce toxic emissions during heating, and the cardiovascular toxicity of these emissions varies greatly due to the heating procedure

About 10% of the worlds population is alcohol- and tobacco-dependent 1-5

Yet it cannot be considered a true laggard like most European countries it is on a downward trend with fewer deaths in 2019 than in 1990 (from 184,466 deaths in 1990 to 143,642 in 2019)