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E-cigarette aerosol is NOT harmless water vapor. The e-cigarette aerosol users breathe from the device and exhale can contain known harmful and potentially harmful substances, including: Nicotine Ultrafine particles that can be inhaled deep into the lungs Flavorings such as diacetyl, a chemical linked to a serious lung disease Volatile organic compounds Cancer-causing chemicals Heavy metals such as nickel, tin, and lead The aerosol users inhale and exhale from e-cigarettes can expose both themselves and bystanders to harmful substances

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Furthermore, we recommend that future studies increase the number of protected areas examined to enhance global representativeness and improve our understanding of cigarette butt contamination patterns and drivers across diverse ecosystems