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En 2012, l'industrie du tabac reste domine par l'oligopole de ces cinq entreprises, le Big Tobacco , dtenant 83 % du march : 43 % par la China National Tobacco Corporation qui en 2012 a produit 2 500 milliards de cigarettes (essentiellement pour le march chinois qui compte 300 millions de fumeurs, soit 30 % du milliard de fumeurs dans le monde), et 40 % par les quatre grandes multinationales du tabac [36]

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Canada was the first country in the world to require cigarette makers put pictorial warnings on cigarette packages, in 2001

This study thus looked at a very large population and the results thus could be trusted to be valid