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The e-liquid usually has constant constituents such as nicotine, propylene glycol, vegetable glycerin, assorted additives, and a mix of flavors

Borgwaldt-KC, Richmond, VA) device was used to collect real-time puffing topography metrics, including puff volume (mL/puff), flow rate (mL/s), peak flow (mL/puff), inter-puff interval (s), puff duration (s), and time of peak (s) for each ENDS user 30,31

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