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Two major proteins of intrinsic apoptosis pathway are apoptosis-related proteins BCL-2 Associated X Protein (BAX) as a proapoptotic protein and B-cell lymphoma 2 (Bcl2) as an antiapoptotic one ( Figure 2I )

[132] Vaccine manufacturers The companies with the highest market share in vaccine production are Merck, Sanofi, GlaxoSmithKline, Pfizer and Novartis, with 70% of vaccine sales concentrated in the EU or US as of 2013

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