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24 These statistics are disheartening, but should not discourage clinicians into thinking they are ineffective in treating tobacco dependence

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Gonzalez-Suarez I, Sewer A, Walker P, Mathis C, Ellis S, Woodhouse H, Guedj E, Dulize R, Marescotti D, Acali S, Martin F, Ivanov NV, Hoeng J, Peitsch MC (2014) Systems biology approach for evaluating the biological impact of environmental toxicants in Vitro

Interestingly, further analyses showed that chemerin DNA methylation was lower in the whole tissues of newborns born to smoking mothers, suggesting that epigenetic mechanisms may be involved in smoke-induced changes to chemerin gene expression