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Counties with statistically significant declines represent a disproportionate share of the population, however, such that 74.4% of the adult male population and 61.1% of the adult female population in 2012 lived in counties where the decline in total cigarette smoking prevalence was statistically significant

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Scientific reviews and regulatory documents have explored how additives affect pyrolysis products, nicotine delivery, and sensory smoothness. This is one reason cigarette discourse so often focuses on chemistry and policy