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The participants were categorized into six groups according to their smoking history and habit change to e-cigarette use: Ex-smokers five or more years since quitting (YSQ) without e-cigarette use Ex-smokers five or more YSQ with e-cigarette use Ex-smokers less than five YSQ without e-cigarette use Ex-smokers less than five YSQ with e-cigarette use Current smokers with e-cigarette use Current smokers without e-cigarette use During follow-up, 53,354 individuals developed lung cancer and there were 6,351 lung cancer-specific deaths

CUL4A induces epithelial-mesenchymal transition and promotes cancer metastasis by regulating ZEB1 expression

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