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Causes of Jaw Pain On One Side Here, we will discuss the reasons that can cause sore jaw muscles: 1.Temporomandibular Disorders Disorders of the jaw muscles, temporomandibular joints, and nerves linked to persistent facial pain are referred to as temporomandibular disorders (TMD) Temporomandibular disorder can be caused by any issue that interferes with the intricate network of muscles, bones, and joints from functioning as a unit