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Continuous smoking abstinence rate Weeks 9-24 (adjusted): Cytisinicline demonstrated a superior efficacy profile compared with varenicline, with aORs ranging from 1.90 to 2.13 across the three sets of treatment effect modifiers

Coculturing nave CD4 + T cells isolated from the spleens of Gpr15 +/+ mice with CSE (0.251%) did not increase IFN- or IL-4 expression, indicating that CSE does not influence their differentiation into Th1 or Th2 cells (Supplementary Fig

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