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[408] JTI acquired R.J

He goes on to describe the sequence of effects typically experienced in the context of the strong tobacco preparation used in the ceremonial or dietary context: The first effects may set in quite immediately or after a few minutes, the onset being experienced either abruptly (an internal blow), or more gradually as an intensifying malaise

Both interact with the body in the same way, binding to nicotine receptors in the brain to produce alertness, calmness, and dependency

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