Elsewhere, the change has been much more dramatic
However, it is important to note that e-cigarettes are not FDA-approved smoking cessation product, and users should consult with their healthcare provider before using e-cigarettes as a quit-smoking aid
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Among studies analyzing risk and protective factors, as well as motives for EC use, arranged from lower to higher quality in study design, there is one case-control study 60 , one discrete choice experiment 63 , 18 cross-sectional studies 47,50-53,55-58,64,66,67,70,71,75,78,79,96 , 8 longitudinal studies 54,61,62,68,74,76,77,80 , and 2 randomized controlled trials 49,59