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Drugs with short half-lives may lead to more frequent use, while those with longer half-lives may stay in the body and potentially lead to cumulative effects over time

The most comprehensive review of e-cigarette interventions shows that the proportion of participants in similar studies (where the full cohort was supplied with e-cigarettes) who had stopped smoking at three-month follow-up was between 19% and 44%, while at 12-month follow-up the rate was between 14% and 53%

Between 1990 and 2019, global smoking prevalence decreased by 27.5% in males (37.7% in females) and global cigarette consumption has declined since 2009 (see figure below)

Only after I left did I realize that the subject of M*A*S*H never came up