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Although the number of cigarette smokers in the US has fallen to one of the lowest levels in history, the proportion who smoke menthols has been increasing, according to the CDC

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Among the other drug efflux ATPase genes previously reported to contribute to cisplatin resistance ABCG2, ABCC2, ABCA1 , and ABCC1 were significantly up-regulated in at least one cell line (Figure S3cf), while ATP7B was unchanged after exposure to e-cigarette aerosol extract (Figure S3g)