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In February 2011, the FDA approved the use of botulinum toxin (BOTOX) for chronic migraine and facial pain as a primary treatment

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BAT clarified that its policy defines hazardous work as including, but not restricted to harvesting, topping and suckering - because [these tasks] may involve exposure to Green Tobacco Sickness (GTS), and accepts that where suitable precautions take place to mitigate GTS, 16 and 17-year-old youth may work, provided that they have safety training and appropriate personal protective equipment (PPE) provided by the farmer prior to commencing work.[128] BAT noted that there is no standard definition of hazardous work in the tobacco industry, and is engaged in an international multi-stakeholder initiative to reach such a definition