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Among them, the representative agent gefapixant has undergone extensive clinical evaluation in chronic cough: a phase IIb trial demonstrated that oral administration of 50 mg twice daily significantly reduced cough frequency (185), and subsequent global phase III studies further confirmed the efficacy and safety of the 45 mg twice-daily regimen (186)

It could be that this rule-breaking leads to the violation of anti-smoking norms, Prof

Our findings suggest that this practice should be continued and may lead to better clinical outcomes, especially in the setting of ACL reconstruction

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