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Cigarette Stains on Enamel: The Combined Effect The combined effect of nicotine and tar on tooth enamel is what creates the characteristic appearance of cigarette stains on enamel , a layered discoloration that includes both surface tar deposits and deeply embedded nicotine pigmentation

Common chronic airway inflammatory diseases include chronic obstructive pulmonary disease (COPD), asthma, allergic rhinitis (AR), non-allergic rhinitis (NAR), chronic rhinosinusitis (CRS), and hypersensitivity pneumonitis (HP), affecting a wide population [1, 2]