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Signs include off smells, crumbling tobacco, discoloration, uneven burn, or visible mold

Cancer Risk Starts Rising Sharply Smoking for 5 years increases: Lung cancer risk by 3040% Throat cancer risk significantly Risk of chronic inflammation and pre-cancerous lesions Breathing Capacity Drops Many smokers experience: Shortness of breath on exertion Wheezing Reduced stamina persistent phlegm HRCT scans often demonstrate early emphysema, airway obstruction, and bronchiolar thickening

At present, only markers of tubular structure/function allow early prediction of cadmium-induced renal tubular dysfunction