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Ritchie Shoemaker, who coined the term Chronic Inflammatory Response Syndrome (CIRS)

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It has also been linked to gasdermin D mediated cell death termed pyroptosis (99)

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9-11 Mechanistically, BPC-157 promotes fibroblast activity, modulates the nitric oxide system, enhances angiogenesis through vascular-endothelial growth factor, downregulates proinflammatory cytokines, and stimulates collagen remodeling (Figure 1)

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10.1038/s41598-018-23672-0 278 VemulaD.JayasuryaP.SushmithaV.KumarY

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