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21, 23 Consider supplementation when the patient is prescribed medications causing folate deficiency, e.g., methotrexate

BPC-157 is a research peptide not approved by Health Canada for human therapeutic use

See the above image to get a basic visual idea of what happens to the spine with lumbar stenosis

Neuronal mitochondrial dysfunction and central hypometabolism not only impair synaptic plasticity in cognitive-related brain regions but also further promote the release of neuronal DAMPs (e.g., mtDNA), which can activate local microglia in the central nervous system, forming a central energy-inflammation positive feedback loop