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Neuroinflammation Neuronal loss in PD is associated with chronic neuroinflammation, which is controlled primarily by microglia, the major resident immune cells in the brain (Perry, 2012)

These results suggest a role in telomere maintenance under experimental conditions

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You will see it stated confidently in a lot of places that the body adapts after 4 to 6 weeks, tolerance builds, and the effect fades, so you have to cycle. It sounds authoritative