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& Karplus, P

Targeting of TAMs: can we be more clever than cancer cells

Patients in BE COMPLETE were randomized 2:1 to SC bimekizumab 160 mg Q4W or placebo (Supplementary Figure S1)

In order to test a possible effect of intracellular glutathione synthesis in such a process, buthionine sulfoximine (BSO), a specific the inhibitor of gamma-glutamylcysteine synthetase, was used to block the first step of intracellular glutathione synthesis