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While Dihexa-specific desensitization kinetics haven't been thoroughly characterized in long-term studies, applying known c-Met receptor regulation patterns suggests daily dosing beyond 46 weeks without rest periods would likely produce diminishing returns

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Potential mechanisms underlying clinical benefits of GLP-1RAs GLP-1 receptors are thought to be expressed on atrial and ventricular cardiomyocytes, endothelial cells in the human heart, and endothelial and smooth muscle cells in blood vessels [21]

Marie-Lyne Nault is an orthopedic surgeon and researcher specializing in pediatric sports medicine in Montreal