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A recent meta-analysis of 16 trials investigated 12 Chinese herbal formulas, three Chinese patent medicines, and one single herbal medicine highlighting both immunological and symptomatic outcomes in HT patients ( Astragalus membranaceus (Fisch.) Bge., Codonopsis pilosula (Franch.) Nannf., Angelica archangelica L., Atractylodes macrocephala Koidz., Ligusticum chuanxiong Hort., Paeonia lactiflora Pall., Curcuma longa L., Poriacocos (Schw.) Wolf., Citrus aurantium L., Pinellia ternata (Thunb.) Makino, Fritillaria thunbergii Miq.) 10 gr twice/day resulted in the best reduction of both TPOAb and TGAb compared to placebo, but changes in clinical symptoms were not evaluated
Regular application of the mercury-rich cream could also lead to rash, skin discolouration and blotching
