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Inhibitory effects of fruit extracts on nitric oxide-induced proliferation in MCF-7 cells

The copper coordination chemistry of GHK-Cu enables controlled cellular copper delivery while preventing the formation of reactive oxygen species characteristic of free copper toxicity, with the peptide's binding affinity (log K = 16.1) positioning it perfectly within the physiological copper transport hierarchy to facilitate controlled metal transfer to enzymatic targets including lysyl oxidase (essential for collagen cross-linking) and superoxide dismutase (critical for antioxidant defense)

In standard research applications, peptides like BPC-157 are typically administered via subcutaneous injection near the injury site to allow for systemic absorption and local regeneration

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