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Description

Another interesting used covalently grafted quaternary ammonium groups (QAGs) containing 12-carbon straight-chain alkanes to the dextran polymer skeleton

Some common examples are shown below

This approach has been exploited recently in several contexts by the development of a series of cationic antioxidants targeted to mitochondria, including derivatives of the endogenous antioxidants ubiquinol (MitoQ), alpha-tocopherol (MitoVit E), and of the synthetic spin trap PBN (MitoPBN