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The most commonly reported side effects in clinical trials include: Nausea Vomiting Diarrhea Constipation Most of these symptoms were mild to moderate and tended to improve over time as the body adjusted to the medication, especially when doses were increased gradually

Studie 6: Redding bij vaatligatie Citatie: Vukojevic J., Siroglavic M., Kasnik K., et al

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To confirm the binding mode between c-MET II and HGF I as shown in our structure, we introduced three point mutations in the K1 domain of HGF, including E159R, E195R, and R197E, to disrupt this interface, and examined the effects of these mutations on c-MET activation