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Contraindications AOD-9604 peptide therapy may not be suitable for individuals who: Are pregnant or breastfeeding Are under the age of 18 Have active or recent malignancy A consultation is required to determine suitability prior to starting therapy

Cost effectiveness of tibial nonunion treatment: a comparison between rhBMP-7 and autologous bone graft in two Italian centres

However, certain symptoms require prompt evaluation: Trouble breathing, noisy breathing, or choking sensations Inability to swallow liquids or solids Rapidly enlarging neck mass, visible swelling, or redness Unexplained weight loss, persistent pain, or bleeding Hoarseness lasting more than two weeks Evaluation begins with a careful history and physical exam