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The D-Nle-Trp-Ile-NH(CH 2 ) 5 CONH 2 analog had intermediate inhibitory activity, and the D-Nle-Met-Ile-NH(CH 2 ) 5 CONH 2 analog showed no ability to effect on Met activation

Common B12 deficiency symptoms include: Persistent fatigue and weakness Tingling or numbness in hands and feet Memory problems and difficulty concentrating Mood changes like irritability or depression Dizziness and balance issues Pale skin or yellowing of eyes Sore, red tongue Who is Most at Risk for B12 Deficiency

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