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Side-effects range from mild (nausea, injection-site discomfort) to serious and even life-threatening (allergic reactions, liver injury, systemic inflammatory response, endotoxin-related events)

This is important during atopic dermatitis therapy because their stimulation increases the production of B, T, and NK lymphocytes, which leads to the restoration of balance between T lymphocytes and consequently alleviates the symptoms of atopic dermatitis, including excessive keratinization and lichenification resulting from intense itching