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ITTs were performed in random-fed mice, early in their light cycle (~0700h0800h) 46

The enzymatic activity of GSAAT(WT) increased by 3.2 and 5.3-fold upon addition of DTT and TRX-f1, respectively, relative to the UT and oxidized protein

Typical doses range from 600 mg to 1,800 mg per day, depending on the condition being treated, and NAC should ideally be taken with food to avoid digestive upset