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Pharmacological characterization of BDNF promoters I, II and IV reveals that serotonin and norepinephrine input is sufficient for transcription activation. The international journal of neuropsychopharmacology vol

(PubMed) Dangour AD, Allen E, Clarke R, et al

The multiple pharmacological treatment options will enhance clinicians ability to identify effective personalised regimens by trying a second medication or combining medications with synergistic or complimentary actions or even escalating treatment to bariatric surgery based on patient preference and underlying comorbidities [7]

Studies suggest it reduces the size of ischemic lesions and supports neural recovery through its BDNF and cerebral circulation-enhancing effects