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[DOI] [PMC free article] [PubMed] [Google Scholar] 6

Animal models, like mice and rats, are essential for studying obesity and testing treatments, though they have limitations due to metabolic differences and ethical concerns (Lakshmanan et al., 2022)

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Animal Model:Ischemia (pMCAO) rats [4] Dosage:100 g/kg Administration:Intraperitoneal injections (i.p.), performed 15 min, 1, 4 and 8 h after permanent middle cerebral artery occlusion (pMCAO)