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Oxidative stress, mitochondrial dysfunction, and neuroinflammation are key contributors to PD pathology, making SF an obvious candidate for therapeutic intervention due to its ability to target these mechanisms

Moreover, no formal publication bias assessment was performed, and therefore studies with null or negative results may be underrepresented

It achieves an ultra-fast clinical onset within 30 to 60 seconds of intravenous administration, making it a primary medication for Rapid Sequence Induction and Intubation (RSII) to secure an immediate airway control

Its safety profile is comparable to a placebo, supporting its repurposing for ASD treatment [91]