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The lack of immunogenicity has practical implications: the peptide can be used for extended periods without loss of efficacy due to antibody neutralization, there is minimal risk of allergic or hypersensitivity reactions, and repeated treatment cycles are supported as prior exposure does not sensitize the immune system

The duration of vitamin B12 effectiveness depends on your health condition and the supplement type, and the severity of your deficiency

Second, larger vials (10-20 mg) generally get the same 2 mL to keep concentration high enough that GLP-1 weekly doses don't require uncomfortably large injection volumes