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Sequence 3: Sandwich method (for sensitive skin) Cleanse Light layer of moisturizer Apply retinol Apply peptide serum Final layer of moisturizer Best for: Reducing retinol irritation while still getting benefits Wait time between layers 1-2 minutes between products is ideal: Allows first product to absorb Prevents pilling or mixing on skin surface Maximizes penetration of each ingredient Don't wait too long: 5+ minutes unnecessary Skin dries out between applications Makes subsequent products harder to spread Morning vs evening application Evening routine (most common approach): Evening: Peptide serum + Retinol + Moisturizer Why: Retinol degrades with sun exposure
the last 10 years or so, Ive had a whole bunch of retrospective projects, which are the kind of thing I normally just run from
doi:10.1681/ASN.2016030278 Heidet L, Gubler M-C
S., Lim, Y
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