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Moreover, the number of senescent cells also increase with culture time, resulting in a loss of division capabilities, resistance to apoptosis, and the acquisition of a robust proinammatory secretome known as the senescence-associated secretory phenotype (SASP) (Jeon et al., 2018)

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Articles in this section explore how these systems interact: Undermethylation & Autism: Interpreting whole-blood histamine and the plasma methylation panel (SAM, SAH, homocysteine) to identify hidden metabolic bottlenecks

10.1002/biof.184 114 TianoL.CarnevaliP.PadellaL.SantoroL.PrincipiF.BrugeF.et al