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Ten tumor-related pathways were primarily enriched for the regulation of cell apoptotic process (4 pathways), cell proliferation (2), cell cycle (1), cell differentiation (1), mesenchyme migration (1), and other terms, such as DNA conformation change (1), suggesting that the ribosome, Wnt, and TGF-1 signaling pathways may promote tumorigenesis by regulating apoptosis (Supplementary Figs